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Gene read counts	Bidirectional read counts	Tfit regions	dREG regions
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Technical details

Sample name	Sample ID	Paper identifier	Protocol	Library prep	Control/Experimental	Wildtype & Untreated	QC score	Replicate
SRR11059463	1086	Johnston2020nascent	PRO-seq	ligation	control	True	2	1
SRR11059464	1087	Johnston2020nascent	PRO-seq	ligation	control	True	2	2
SRR11059465	1088	Johnston2020nascent	PRO-seq	ligation	experimental	False	2	1
SRR11059466	1089	Johnston2020nascent	PRO-seq	ligation	experimental	False	2	2
SRR11059467	1090	Johnston2020nascent	PRO-seq	ligation	experimental	False	1	1
SRR11059468	1091	Johnston2020nascent	PRO-seq	ligation	experimental	False	2	2
SRR11059469	1092	Johnston2020nascent	PRO-seq	ligation	experimental	False	2	1
SRR11059470	1093	Johnston2020nascent	PRO-seq	ligation	experimental	False	2	2

Cellular details

Sample name	Organism	Sample type	Cell type	Clone/Individual	Strain	Genotype	Construct
SRR11059463	H. sapiens	cell line	THP1
SRR11059464	H. sapiens	cell line	THP1
SRR11059465	H. sapiens	cell line	THP1
SRR11059466	H. sapiens	cell line	THP1
SRR11059467	H. sapiens	cell line	THP1
SRR11059468	H. sapiens	cell line	THP1
SRR11059469	H. sapiens	cell line	THP1
SRR11059470	H. sapiens	cell line	THP1

Conditions

Sample name	Condition type	Treatment	Start time	End time	Duration
SRR11059463	no treatment		None	None	None
SRR11059464	no treatment		None	None	None
SRR11059465	treatment	INCB059872 (25 nM)	-24 hr	0 hr	1 day
SRR11059466	treatment	INCB059872 (25 nM)	-24 hr	0 hr	1 day
SRR11059467	treatment	INCB059872 (25 nM)	-12 hr	0 hr	12 hr
SRR11059468	treatment	INCB059872 (25 nM)	-12 hr	0 hr	12 hr
SRR11059469	treatment	INCB059872 (25 nM)	-6 hr	0 hr	6 hr
SRR11059470	treatment	INCB059872 (25 nM)	-6 hr	0 hr	6 hr

Sample metrics

Sample name	Raw read length	Trim read depth	Duplication proportion	Proportion reads mapped	Exon/intron ratio	Unique read proportion	Sample QC score	Sample NRO score
SRR11059463	75	45,454,197	0.59576	0.9082	4.2343	0.52207	2	2
SRR11059464	75	45,488,224	0.56365	0.9017	3.9376	0.56103	2	2
SRR11059465	75	28,579,662	0.57024	0.9066	4.30812	0.50724	2	2
SRR11059466	75	36,244,327	0.60834	0.9017	4.25108	0.49797	2	2
SRR11059467	75	26,205,634	0.49015	0.9145	3.8374	0.57522	1	2
SRR11059468	75	20,874,664	0.50058	0.9051	4.11807	0.54783	2	2
SRR11059469	75	25,431,836	0.56306	0.9098	4.31376	0.50279	2	2
SRR11059470	75	19,434,787	0.55582	0.9051	4.47579	0.48587	2	2

Bidirectionals

Sample name	Tfit total bidirs	Tfit promoter bidirs	Tfit intronic bidirs	Tfit intergenic bidirs	dREG total bidirs	dREG promoter bidirs	dREG intronic bidirs	dREG intergenic bidirs
SRR11059463	52519	14211	22536	15416	44726	11671	19531	13329
SRR11059464	50733	13854	21838	14672	43212	11510	18804	12602
SRR11059465	47409	12325	20708	13784	38426	11558	16089	10980
SRR11059466	48449	12747	21141	13896	39175	11473	16470	11286
SRR11059467	42999	11951	18387	12151	35299	11210	14624	9726
SRR11059468	40654	11456	17380	11273	32623	11121	13251	8632
SRR11059469	42876	12001	18450	12003	34547	11217	14246	9365
SRR11059470	38211	10854	16661	10132	30026	10902	11913	7619