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Technical details

Sample name	Sample ID	Paper identifier	Protocol	Library prep	Control/Experimental	Wildtype & Untreated	QC score	Replicate
SRZ5861742	1234	Kourtis2018oncogenic	GRO-seq	not noted in GEO or publication	control	True	4	1
SRZ5861744	1235	Kourtis2018oncogenic	GRO-seq	not noted in GEO or publication	control	True	4	2
SRZ5861746	1236	Kourtis2018oncogenic	GRO-seq	not noted in GEO or publication	control	True	4	3
SRZ5861748	1237	Kourtis2018oncogenic	GRO-seq	not noted in GEO or publication	experimental	False	4	1
SRZ5861750	1238	Kourtis2018oncogenic	GRO-seq	not noted in GEO or publication	experimental	False	4	2
SRZ5861752	1239	Kourtis2018oncogenic	GRO-seq	not noted in GEO or publication	experimental	False	3	3
SRZ5861754	1240	Kourtis2018oncogenic	GRO-seq	not noted in GEO or publication	experimental	False	4	1
SRZ5861756	1241	Kourtis2018oncogenic	GRO-seq	not noted in GEO or publication	experimental	False	4	2
SRZ5861758	1242	Kourtis2018oncogenic	GRO-seq	not noted in GEO or publication	experimental	False	3	3
SRZ5861760	1243	Kourtis2018oncogenic	GRO-seq	not noted in GEO or publication	experimental	False	4	1
SRZ5861762	1244	Kourtis2018oncogenic	GRO-seq	not noted in GEO or publication	experimental	False	3	2
SRZ5861764	1245	Kourtis2018oncogenic	GRO-seq	not noted in GEO or publication	experimental	False	3	3
SRZ5861766	1246	Kourtis2018oncogenic	GRO-seq	not noted in GEO or publication	experimental	False	3	1
SRZ5861768	1247	Kourtis2018oncogenic	GRO-seq	not noted in GEO or publication	experimental	False	4	2
SRZ5861770	1248	Kourtis2018oncogenic	GRO-seq	not noted in GEO or publication	experimental	False	4	3
SRZ5861772	1249	Kourtis2018oncogenic	GRO-seq	not noted in GEO or publication	experimental	False	3	1
SRZ5861774	1250	Kourtis2018oncogenic	GRO-seq	not noted in GEO or publication	experimental	False	4	2
SRZ5861776	1251	Kourtis2018oncogenic	GRO-seq	not noted in GEO or publication	experimental	False	3	3
SRZ5861778	1252	Kourtis2018oncogenic	GRO-seq	not noted in GEO or publication	experimental	False	4	1
SRZ5861780	1253	Kourtis2018oncogenic	GRO-seq	not noted in GEO or publication	experimental	False	3	2
SRZ5861782	1254	Kourtis2018oncogenic	GRO-seq	not noted in GEO or publication	experimental	False	3	3
SRZ5861784	1255	Kourtis2018oncogenic	GRO-seq	not noted in GEO or publication	experimental	False	3	1
SRZ5861786	1256	Kourtis2018oncogenic	GRO-seq	not noted in GEO or publication	experimental	False	4	2
SRZ5861788	1257	Kourtis2018oncogenic	GRO-seq	not noted in GEO or publication	experimental	False	3	3
SRZ5861790	1258	Kourtis2018oncogenic	GRO-seq	not noted in GEO or publication	experimental	False	3	1
SRZ5861792	1259	Kourtis2018oncogenic	GRO-seq	not noted in GEO or publication	experimental	False	4	2
SRZ5861794	1260	Kourtis2018oncogenic	GRO-seq	not noted in GEO or publication	experimental	False	3	3
SRZ5861796	1261	Kourtis2018oncogenic	GRO-seq	not noted in GEO or publication	experimental	False	3	1
SRZ5861798	1262	Kourtis2018oncogenic	GRO-seq	not noted in GEO or publication	experimental	False	3	2
SRZ5861800	1263	Kourtis2018oncogenic	GRO-seq	not noted in GEO or publication	experimental	False	3	3

Cellular details

Sample name	Organism	Sample type	Cell type	Clone/Individual	Strain	Genotype	Construct
SRZ5861742	H. sapiens	cell line	CUTLL1
SRZ5861744	H. sapiens	cell line	CUTLL1
SRZ5861746	H. sapiens	cell line	CUTLL1
SRZ5861748	H. sapiens	cell line	CUTLL1
SRZ5861750	H. sapiens	cell line	CUTLL1
SRZ5861752	H. sapiens	cell line	CUTLL1
SRZ5861754	H. sapiens	cell line	CUTLL1
SRZ5861756	H. sapiens	cell line	CUTLL1
SRZ5861758	H. sapiens	cell line	CUTLL1
SRZ5861760	H. sapiens	cell line	CUTLL1
SRZ5861762	H. sapiens	cell line	CUTLL1
SRZ5861764	H. sapiens	cell line	CUTLL1
SRZ5861766	H. sapiens	cell line	CUTLL1
SRZ5861768	H. sapiens	cell line	CUTLL1
SRZ5861770	H. sapiens	cell line	CUTLL1
SRZ5861772	H. sapiens	cell line	CUTLL1
SRZ5861774	H. sapiens	cell line	CUTLL1
SRZ5861776	H. sapiens	cell line	CUTLL1
SRZ5861778	H. sapiens	cell line	CUTLL1
SRZ5861780	H. sapiens	cell line	CUTLL1
SRZ5861782	H. sapiens	cell line	CUTLL1
SRZ5861784	H. sapiens	cell line	CUTLL1
SRZ5861786	H. sapiens	cell line	CUTLL1
SRZ5861788	H. sapiens	cell line	CUTLL1
SRZ5861790	H. sapiens	cell line	CUTLL1
SRZ5861792	H. sapiens	cell line	CUTLL1
SRZ5861794	H. sapiens	cell line	CUTLL1
SRZ5861796	H. sapiens	cell line	CUTLL1
SRZ5861798	H. sapiens	cell line	CUTLL1
SRZ5861800	H. sapiens	cell line	CUTLL1

Conditions

Sample name	Condition type	Treatment	Start time	End time	Duration
SRZ5861742	vehicle	DMSO	None	None	None
SRZ5861744	vehicle	DMSO	None	None	None
SRZ5861746	vehicle	DMSO	None	None	None
SRZ5861748	treatment	gamma-secretase inhibitor (1 microM)	-72 hr	0 hr	3 day
SRZ5861750	treatment	gamma-secretase inhibitor (1 microM)	-72 hr	0 hr	3 day
SRZ5861752	treatment	gamma-secretase inhibitor (1 microM)	-72 hr	0 hr	3 day
SRZ5861754	treatment	gamma-secretase inhibitor (1 microM)	-4325 min	-5 min	3 day
SRZ5861756	treatment	gamma-secretase inhibitor (1 microM)	-4325 min	-5 min	3 day
SRZ5861758	treatment	gamma-secretase inhibitor (1 microM)	-4325 min	-5 min	3 day
SRZ5861760	treatment	gamma-secretase inhibitor (1 microM)	-4330 min	-10 min	3 day
SRZ5861762	treatment	gamma-secretase inhibitor (1 microM)	-4330 min	-10 min	3 day
SRZ5861764	treatment	gamma-secretase inhibitor (1 microM)	-4330 min	-10 min	3 day
SRZ5861766	treatment	gamma-secretase inhibitor (1 microM)	-4340 min	-20 min	3 day
SRZ5861768	treatment	gamma-secretase inhibitor (1 microM)	-4340 min	-20 min	3 day
SRZ5861770	treatment	gamma-secretase inhibitor (1 microM)	-4340 min	-20 min	3 day
SRZ5861772	treatment	gamma-secretase inhibitor (1 microM)	-4360 min	-40 min	3 day
SRZ5861774	treatment	gamma-secretase inhibitor (1 microM)	-4360 min	-40 min	3 day
SRZ5861776	treatment	gamma-secretase inhibitor (1 microM)	-4360 min	-40 min	3 day
SRZ5861778	treatment	gamma-secretase inhibitor (1 microM)	-4400 min	-80 min	3 day
SRZ5861780	treatment	gamma-secretase inhibitor (1 microM)	-4400 min	-80 min	3 day
SRZ5861782	treatment	gamma-secretase inhibitor (1 microM)	-4400 min	-80 min	3 day
SRZ5861784	treatment	gamma-secretase inhibitor (1 microM)	-4480 min	-160 min	3 day
SRZ5861786	treatment	gamma-secretase inhibitor (1 microM)	-4480 min	-160 min	3 day
SRZ5861788	treatment	gamma-secretase inhibitor (1 microM)	-4480 min	-160 min	3 day
SRZ5861790	treatment	gamma-secretase inhibitor (1 microM)	-4640 min	-320 min	3 day
SRZ5861792	treatment	gamma-secretase inhibitor (1 microM)	-4640 min	-320 min	3 day
SRZ5861794	treatment	gamma-secretase inhibitor (1 microM)	-4640 min	-320 min	3 day
SRZ5861796	treatment	gamma-secretase inhibitor (1 microM)	-4960 min	-640 min	3 day
SRZ5861798	treatment	gamma-secretase inhibitor (1 microM)	-4960 min	-640 min	3 day
SRZ5861800	treatment	gamma-secretase inhibitor (1 microM)	-4960 min	-640 min	3 day

Sample metrics

Sample name	Raw read length	Trim read depth	Duplication proportion	Proportion reads mapped	Exon/intron ratio	Unique read proportion	Sample QC score	Sample NRO score
SRZ5861742	51	9,543,647	0.43306	0.9592	3.92929	0.55947	4	2
SRZ5861744	51	8,523,813	0.36344	0.9563	3.28664	0.61446	4	2
SRZ5861746	51	8,240,327	0.38221	0.9568	3.33818	0.59907	4	2
SRZ5861748	51	8,091,019	0.4317	0.9535	3.31955	0.54239	4	2
SRZ5861750	51	8,144,520	0.44285	0.9545	3.28077	0.53412	4	2
SRZ5861752	51	11,302,385	0.4498	0.9532	3.53372	0.55318	3	2
SRZ5861754	51	9,951,819	0.47341	0.9506	3.98616	0.52126	4	2
SRZ5861756	51	9,925,917	0.46718	0.9458	3.99654	0.52783	4	2
SRZ5861758	51	11,201,643	0.41913	0.9515	3.70286	0.5836	3	2
SRZ5861760	51	8,606,229	0.41387	0.9476	3.59732	0.55878	4	2
SRZ5861762	51	10,006,886	0.40617	0.953	3.51227	0.5894	3	2
SRZ5861764	51	11,089,624	0.43622	0.9558	3.77551	0.5659	3	2
SRZ5861766	51	10,768,579	0.38192	0.948	3.46006	0.61841	3	2
SRZ5861768	51	9,718,672	0.34947	0.9535	3.29107	0.64265	4	2
SRZ5861770	51	8,744,642	0.34684	0.9541	3.37179	0.63574	4	2
SRZ5861772	51	11,415,682	0.37822	0.9507	3.43117	0.62625	3	2
SRZ5861774	51	8,780,830	0.38367	0.9549	3.34899	0.60151	4	2
SRZ5861776	51	10,130,431	0.39564	0.9514	3.58912	0.60075	3	2
SRZ5861778	51	8,792,431	0.39504	0.9548	3.62199	0.59016	4	2
SRZ5861780	51	11,253,150	0.39474	0.9561	3.58491	0.60887	3	2
SRZ5861782	51	12,092,224	0.42666	0.9535	3.784	0.58015	3	2
SRZ5861784	51	10,868,842	0.43222	0.9567	3.62537	0.56898	3	2
SRZ5861786	51	9,830,286	0.40226	0.9557	3.52665	0.59214	4	2
SRZ5861788	51	11,870,658	0.43853	0.955	3.66298	0.56758	3	2
SRZ5861790	51	11,572,573	0.43349	0.9547	3.85635	0.57168	3	2
SRZ5861792	51	9,548,023	0.41319	0.9557	3.56908	0.57968	4	2
SRZ5861794	51	10,432,191	0.37477	0.9547	3.42614	0.62315	3	2
SRZ5861796	51	10,164,214	0.38743	0.9503	3.14118	0.60865	3	2
SRZ5861798	51	11,599,122	0.6723	0.9622	5.21076	0.32983	3	3
SRZ5861800	51	10,958,488	0.39749	0.9549	3.39276	0.60443	3	2

Bidirectionals

Sample name	Tfit total bidirs	Tfit promoter bidirs	Tfit intronic bidirs	Tfit intergenic bidirs	dREG total bidirs	dREG promoter bidirs	dREG intronic bidirs	dREG intergenic bidirs
SRZ5861742	11620	4465	5146	1151	4947	2673	1607	636
SRZ5861744	11204	3886	5150	1240	4445	2306	1501	596
SRZ5861746	10334	4117	4488	1051	4526	2511	1408	574
SRZ5861748	8008	2516	3620	1109	2856	1318	1073	516
SRZ5861750	8206	2813	3556	1081	3119	1506	1089	546
SRZ5861752	11350	4496	4721	1435	5575	2953	1803	807
SRZ5861754	13346	5254	5763	1557	5932	3173	2008	806
SRZ5861756	12026	4489	5248	1448	5214	2757	1768	750
SRZ5861758	14599	5872	6205	1881	7162	3721	2466	1068
SRZ5861760	13275	4915	5935	1619	5727	2957	2012	840
SRZ5861762	14559	5896	6135	1787	6944	3714	2283	948
SRZ5861764	14946	6094	6325	1820	7410	3989	2483	1003
SRZ5861766	13773	5711	5758	1552	6908	3768	2244	817
SRZ5861768	13404	5437	5705	1519	6466	3541	2145	800
SRZ5861770	12684	5042	5350	1455	5904	3257	1934	707
SRZ5861772	13544	5841	5522	1418	7281	3991	2391	872
SRZ5861774	10637	4143	4498	1154	4933	2682	1615	610
SRZ5861776	11978	4794	5038	1373	6066	3297	1939	762
SRZ5861778	10333	3960	4409	1199	4552	2384	1537	619
SRZ5861780	13448	5344	5571	1693	6910	3694	2241	963
SRZ5861782	13266	5445	5230	1716	7330	4009	2310	952
SRZ5861784	11886	4755	5116	1212	5557	2946	1833	704
SRZ5861786	11134	4309	4760	1184	5020	2647	1658	637
SRZ5861788	13210	5406	5466	1399	6529	3529	2072	819
SRZ5861790	11502	4486	5023	1153	5880	3165	1884	731
SRZ5861792	10315	3941	4376	1183	4887	2567	1614	661
SRZ5861794	11508	4615	4878	1274	6048	3282	1954	758
SRZ5861796	10992	4365	4638	1213	5599	3016	1751	697
SRZ5861798	6577	2416	2756	506	2695	1478	814	313
SRZ5861800	11661	4622	4927	1266	5988	3242	1885	751