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Gene read counts	Bidirectional read counts	Tfit regions	dREG regions
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Technical details

Sample name	Sample ID	Paper identifier	Protocol	Library prep	Control/Experimental	Wildtype & Untreated	QC score	Replicate
SRR10312745	1486	Li2020human	PRO-seq	ligation	experimental	False	2	1
SRR10312746	1487	Li2020human	PRO-seq	ligation	experimental	False	3	1
SRR10312747	1488	Li2020human	PRO-seq	ligation	experimental	False	2	1
SRR10312748	1489	Li2020human	PRO-seq	ligation	experimental	False	3	1
SRR10312749	1490	Li2020human	PRO-seq	ligation	experimental	False	3	1
SRR10312750	1491	Li2020human	PRO-seq	ligation	experimental	False	3	1
SRR10312751	1492	Li2020human	PRO-seq	ligation	experimental	False	3	1
SRR10312752	1493	Li2020human	PRO-seq	ligation	experimental	False	3	1
SRR10312753	1494	Li2020human	PRO-seq	ligation	experimental	False	4	1
SRR10312754	1495	Li2020human	PRO-seq	ligation	experimental	False	3	1
SRR10312755	1496	Li2020human	PRO-seq	ligation	experimental	False	3	1
SRR10312756	1497	Li2020human	PRO-seq	ligation	experimental	False	4	1
SRR10312757	1498	Li2020human	PRO-seq	ligation	experimental	False	4	2
SRR10312758	1499	Li2020human	PRO-seq	ligation	experimental	False	5	2
SRR10312759	1500	Li2020human	PRO-seq	ligation	experimental	False	3	1
SRR10312760	1501	Li2020human	PRO-seq	ligation	experimental	False	4	1
SRR10312761	1502	Li2020human	PRO-seq	ligation	experimental	False	3	1
SRR10312762	1503	Li2020human	PRO-seq	ligation	experimental	False	3	1
SRR10312763	1504	Li2020human	PRO-seq	ligation	experimental	False	4	1
SRR10760415	1505	Li2020human	PRO-seq	ligation	experimental	False	4	1
SRR10760416	1506	Li2020human	PRO-seq	ligation	experimental	False	4	1
SRR10760417	1507	Li2020human	PRO-seq	ligation	experimental	False	4	1

Cellular details

Sample name	Organism	Sample type	Cell type	Clone/Individual	Strain	Genotype	Construct
SRR10312745	H. sapiens	primary cell	foreskin fibroblast
SRR10312746	H. sapiens	primary cell	foreskin fibroblast
SRR10312747	H. sapiens	primary cell	foreskin fibroblast
SRR10312748	H. sapiens	primary cell	foreskin fibroblast
SRR10312749	H. sapiens	primary cell	foreskin fibroblast
SRR10312750	H. sapiens	primary cell	foreskin fibroblast
SRR10312751	H. sapiens	primary cell	foreskin fibroblast
SRR10312752	H. sapiens	primary cell	foreskin fibroblast
SRR10312753	H. sapiens	primary cell	foreskin fibroblast
SRR10312754	H. sapiens	primary cell	foreskin fibroblast
SRR10312755	H. sapiens	primary cell	foreskin fibroblast
SRR10312756	H. sapiens	primary cell	foreskin fibroblast
SRR10312757	H. sapiens	primary cell	foreskin fibroblast
SRR10312758	H. sapiens	primary cell	foreskin fibroblast
SRR10312759	H. sapiens	primary cell	foreskin fibroblast
SRR10312760	H. sapiens	primary cell	foreskin fibroblast
SRR10312761	H. sapiens	primary cell	foreskin fibroblast
SRR10312762	H. sapiens	primary cell	foreskin fibroblast
SRR10312763	H. sapiens	primary cell	foreskin fibroblast
SRR10760415	H. sapiens	primary cell	foreskin fibroblast
SRR10760416	H. sapiens	primary cell	foreskin fibroblast
SRR10760417	H. sapiens	primary cell	foreskin fibroblast

Conditions

Sample name	Condition type	Treatment	Start time	End time	Duration
SRR10312745	vehicle	DMSO	-6 hr	0 hr	6 hr
	treatment	HCMV strain Towne IE2 BAC (MOI 3)	-96 hr	0 hr	4 day
SRR10312746	treatment	HCMV strain Towne IE2 BAC (MOI 3)	-96 hr	0 hr	4 day
	treatment	dTag7 (200 nM)	-6 hr	0 hr	6 hr
SRR10312747	vehicle	DMSO	-6 hr	0 hr	6 hr
	treatment	HCMV strain Towne IE2F BAC (MOI 3)	-96 hr	0 hr	4 day
SRR10312748	treatment	HCMV strain Towne IE2F BAC (MOI 3)	-96 hr	0 hr	4 day
	treatment	dTag7 (200 nM)	-6 hr	0 hr	6 hr
SRR10312749	vehicle	DMSO	-6 hr	0 hr	6 hr
	treatment	HCMV strain Towne IE2 BAC (MOI 3)	-96 hr	0 hr	4 day
	treatment	flavopiridol (1 microM)	-1 hr	0 hr	1 hr
SRR10312750	treatment	HCMV strain Towne IE2 BAC (MOI 3)	-96 hr	0 hr	4 day
	treatment	dTag7 (200 nM)	-6 hr	0 hr	6 hr
	treatment	flavopiridol (1 microM)	-1 hr	0 hr	1 hr
SRR10312751	vehicle	DMSO	-6 hr	0 hr	6 hr
	treatment	HCMV strain Towne IE2F BAC (MOI 3)	-96 hr	0 hr	4 day
	treatment	flavopiridol (1 microM)	-1 hr	0 hr	1 hr
SRR10312752	treatment	HCMV strain Towne IE2F BAC (MOI 3)	-96 hr	0 hr	4 day
	treatment	dTag7 (200 nM)	-6 hr	0 hr	6 hr
	treatment	flavopiridol (1 microM)	-1 hr	0 hr	1 hr
SRR10312753	vehicle	DMSO	-6 hr	0 hr	6 hr
	treatment	HCMV strain TB40/E IE2F (MOI 3)	-72 hr	0 hr	3 day
SRR10312754	treatment	HCMV strain TB40/E IE2F (MOI 3)	-72 hr	0 hr	3 day
	treatment	dTag7 (200 nM)	-6 hr	0 hr	6 hr
SRR10312755	vehicle	DMSO	-6 hr	0 hr	6 hr
	treatment	HCMV strain TB40/E IE2F (MOI 3)	-72 hr	0 hr	3 day
	treatment	flavopiridol (1 microM)	-1 hr	0 hr	1 hr
SRR10312756	treatment	HCMV strain TB40/E IE2F (MOI 3)	-72 hr	0 hr	3 day
	treatment	dTag7 (200 nM)	-6 hr	0 hr	6 hr
	treatment	flavopiridol (1 microM)	-1 hr	0 hr	1 hr
SRR10312757	vehicle	DMSO	-6 hr	0 hr	6 hr
	treatment	HCMV strain TB40/E IE2F (MOI 3)	-72 hr	0 hr	3 day
SRR10312758	treatment	HCMV strain TB40/E IE2F (MOI 3)	-72 hr	0 hr	3 day
	treatment	dTag7 (200 nM)	-6 hr	0 hr	6 hr
SRR10312759	vehicle	DMSO	-6 hr	0 hr	6 hr
	treatment	HCMV strain TB40/E IE2F (MOI 3)	-72 hr	0 hr	3 day
	treatment	phosphonoformic acid (400 microg/mL)	-6 hr	0 hr	6 hr
SRR10312760	treatment	HCMV strain TB40/E IE2F (MOI 3)	-72 hr	0 hr	3 day
	treatment	dTag7 (200 nM)	-6 hr	0 hr	6 hr
	treatment	phosphonoformic acid (400 microg/mL)	-6 hr	0 hr	6 hr
SRR10312761	treatment	HCMV strain TB40/E IE2 (MOI 3)	-24 hr	0 hr	1 day
SRR10312762	treatment	HCMV strain TB40/E IE2 (MOI 3)	-72 hr	0 hr	3 day
SRR10312763	treatment	HCMV strain TB40/E IE2 (MOI 3)	-72 hr	0 hr	3 day
	treatment	phosphonoformic acid (400 microg/mL)	-72 hr	0 hr	3 day
SRR10760415	treatment	HCMV strain TB40/E IE2 (MOI 3)	-24 hr	0 hr	1 day
	treatment	flavopiridol (1 microM)	-1 hr	0 hr	1 hr
SRR10760416	treatment	HCMV strain TB40/E IE2 (MOI 3)	-72 hr	0 hr	3 day
	treatment	flavopiridol (1 microM)	-1 hr	0 hr	1 hr
SRR10760417	treatment	HCMV strain TB40/E IE2 (MOI 3)	-72 hr	0 hr	3 day
	treatment	flavopiridol (1 microM)	-1 hr	0 hr	1 hr
	treatment	phosphonoformic acid (400 microg/mL)	-72 hr	0 hr	3 day

Sample metrics

Sample name	Raw read length	Trim read depth	Duplication proportion	Proportion reads mapped	Exon/intron ratio	Unique read proportion	Sample QC score	Sample NRO score
SRR10312745	151	28,131,938	0.57284	0.4631	2.99598	0.36597	2	1
SRR10312746	151	29,148,507	0.34658	0.3919	2.69482	0.58862	3	1
SRR10312747	151	29,341,104	0.45612	0.4495	3.00754	0.47739	2	2
SRR10312748	151	25,042,873	0.45389	0.4444	2.92201	0.47861	3	1
SRR10312749	151	27,133,830	0.60316	0.4143	3.97455	0.24342	3	2
SRR10312750	151	27,986,259	0.58077	0.4429	3.84498	0.26092	3	2
SRR10312751	151	28,029,015	0.61105	0.4359	4.04516	0.24641	3	2
SRR10312752	151	30,551,205	0.63498	0.4659	4.2648	0.23219	3	2
SRR10312753	151	37,734,090	0.12682	0.206	2.90064	0.76371	4	1
SRR10312754	151	43,158,204	0.16795	0.2241	3.0597	0.72562	3	2
SRR10312755	151	40,096,743	0.47187	0.2176	2.4845	0.23985	3	1
SRR10312756	151	36,164,617	0.52805	0.1798	2.58861	0.19099	4	1
SRR10312757	151	38,160,104	0.22618	0.1757	3.18182	0.65076	4	2
SRR10312758	151	25,975,978	0.35778	0.1263	3.20455	0.48307	5	2
SRR10312759	151	41,680,747	0.18489	0.2018	2.89041	0.70178	3	1
SRR10312760	151	39,194,105	0.28535	0.1534	2.98158	0.5768	4	1
SRR10312761	151	35,954,279	0.71422	0.2504	2.78431	0.22871	3	1
SRR10312762	151	33,408,626	0.68796	0.2987	3.20357	0.23976	3	2
SRR10312763	151	24,323,585	0.6958	0.2216	2.85616	0.20881	4	1
SRR10760415	151	36,224,075	0.76692	0.2564	3.86325	0.11142	4	2
SRR10760416	151	30,533,064	0.70274	0.2085	3.36559	0.11848	4	2
SRR10760417	151	35,360,192	0.78925	0.2298	3.95833	0.1056	4	2

Bidirectionals

Sample name	Tfit total bidirs	Tfit promoter bidirs	Tfit intronic bidirs	Tfit intergenic bidirs	dREG total bidirs	dREG promoter bidirs	dREG intronic bidirs	dREG intergenic bidirs
SRR10312745	12889	6837	4816	972	3010	2039	750	353
SRR10312746	18481	10035	6902	1533	6631	4630	1744	515
SRR10312747	16050	8313	5968	1325	4957	3372	1301	493
SRR10312748	15479	8344	5636	1252	5038	3565	1242	450
SRR10312749	11124	6856	4025	684	5654	4499	1290	365
SRR10312750	11525	7108	4211	642	6228	4907	1498	410
SRR10312751	11997	7428	4305	709	6800	5350	1599	430
SRR10312752	13173	8123	4788	790	7901	6098	1974	490
SRR10312753	13870	6292	5499	1499	4078	2477	1294	450
SRR10312754	15408	7564	5891	1448	5240	3222	1659	478
SRR10312755	2097	935	769	206	578	166	109	251
SRR10312756	1446	639	494	155	351	99	41	179
SRR10312757	11890	5451	4739	1147	2922	1747	920	321
SRR10312758	4401	1831	1671	405	452	233	110	102
SRR10312759	14364	6893	5733	1275	4525	2768	1439	405
SRR10312760	10399	4804	4143	844	1983	1176	615	221
SRR10312761	3048	1112	1183	234	313	144	50	89
SRR10312762	4319	1679	1629	368	558	274	125	148
SRR10312763	1342	499	464	116	156	47	19	68
SRR10760415	916	352	320	52	229	53	46	100
SRR10760416	886	374	303	94	205	52	28	109
SRR10760417	824	343	253	75	184	37	25	97